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Siopel® Cream

Siopel® cream is useful whenever the skin needs to be protected from water-soluble or external irritants.

Product Indication

Siopel® Cream contains two active ingredients, cetrimide and dimeticone.  Cetrimide is an antiseptic which destroys a wide range of bacteria (germs), including those found in wounds, whilst dimeticone protects the skin from water.

Siopel® cream is therefore useful whenever the skin needs to be protected from water-soluble irritants or external irritants.

How to Use Siopel® Cream:

  • Wash and dry the skin.  Apply the cream sparingly and massage well into the skin.
  • Apply three to five times daily for the first three to four days. Then, once or twice daily.
  • Do not use on skin that is acutely inflamed or weeping, or before the skin has been cleansed of irritants, such as dirt.

Where to Obtain Siopel® Cream:

Siopel® Cream can be bought at your local pharmacy and is also available on prescription from your doctor.

Product Information:

Siopel® Cream contains Arachis oil (peanut oil) and should not be applied by patients known to be allergic to peanut.  As there is a possible relationship between allergy to peanut and allergy to soya, patients with soya allergy should also avoid Siopel® Cream.

Due to regulatory changes, the content of the Patient Information Leaflet (Revised April 2019) may vary from the one found in your medicine pack.  Please compare the ‘Leaflet prepared/revised date’ towards the end of the leaflet in your pack, with the date on the document below, to establish if there have been any changes.

Pack Sizes

50g tube

Active Ingredients

Strong Cetrimide Solution, 0.75% v/w
Dimeticone 1000, 10% w/w

Adverse Effects

Adverse events should be reported. Reporting forms and information can be found at Adverse events should also be reported to Derma UK on +44 (0)191 375 9020

Certificate of Authenticity

COVID-19 :
Derma UK have been monitoring and will continue to monitor the COVID-19 situation closely. Because of the support and commitment of the Team, and that many of us are working from home, we are able to maintain continuity of service to you and your patients. Our website at  is fully operational and provides a wealth of information on our products. Derma UK continue to support public access to our cosmetic and many of our GSL products via our webshop at  Our thoughts are with those affected and we thank and support the Healthcare Professionals who are going above and beyond to care for the rest of us. Thank you for your business and support during these challenging times. Please feel free to contact us any time with your questions or concerns.